Ethyl 2-(6-nitropyridin-3-yl)acetate → Ethyl 2-(6-aminopyridin-3-yl)acetate
반응식
[N+:1]([C:4]1[N:9]=[CH:8][C:7]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:6][CH:5]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[N:9]=[CH:8][C:7]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:6][CH:5]=1참가 물질
4
실험 절차
A mixture of ethyl (6-nitropyridin-3-yl)acetate (0.9 g, 4.28 mmol), Pd/C (10%, 0.1 g) in MeOH (50 mL) was stirred for 2 hours under H2 atmosphere at room temperature. The mixture was filtered and concentrated to give ethyl (6-aminopyridin-3-yl)acetate.
후처리
- filtrationThe mixture was filtered
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-7101d261f4084c24a316a60c737135f8
- 출처 데이터셋
- uspto-grants-2015_12
- 특허 번호
- US09206199B2
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