3-Oxabicyclo[3.1.0]hexane-6-carboxylic acid → N-(7-(4-methylpyridin-3-yl)isoquinolin-3-yl)-3-oxabicyclo[3.1.0]hexane-6-carboxamide

HRID 1502349노트

반응식

HRID 1502349 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[C:8]1[CH:17]=[C:16]2[C:11]([CH:12]=[C:13]([NH2:18])[N:14]=[CH:15]2)=[CH:10][CH:9]=1.[CH:19]12[CH:24]([C:25](O)=[O:26])[CH:23]1[CH2:22][O:21][CH2:20]2>>[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[C:8]1[CH:17]=[C:16]2[C:11]([CH:12]=[C:13]([NH:18][C:25]([CH:24]3[CH:23]4[CH:19]3[CH2:20][O:21][CH2:22]4)=[O:26])[N:14]=[CH:15]2)=[CH:10][CH:9]=1

참가 물질

3

반응물 2

HCID 122044223-Oxabicyclo[3.1.0]hexane-6-carboxylic acidHCID 679741997-(4-Methylpyridin-3-yl)isoquinolin-3-amine

생성물 1

HCID 57411443N-(7-(4-methylpyridin-3-yl)isoquinolin-3-yl)-3-oxabicyclo[3.1.0]hexane-6-carboxamide

실험 절차

The title compound was prepared following a procedure similar to example 98 using 7-(4-methylpyridin-3-yl)isoquinolin-3-amine and 3-oxabicyclo[3.1.0]hexane-6-carboxylic acid.

출처 및 근거

ORD 기록
ord-c3d5383be68146398ec27771f7259b77
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09206175B2

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