L-(+)-Cysteine → HCID 57312911, 화합물
반응식
[NH2:1][C@H:2]([C:5]([OH:7])=[O:6])[CH2:3][SH:4].[C:8]([O:12][CH2:13][CH3:14])(=[O:11])[CH:9]=O>O>[CH3:14][CH2:13][O:12][C:8]([CH:9]1[NH:1][CH:2]([C:5]([OH:7])=[O:6])[CH2:3][S:4]1)=[O:11]참가 물질
4
실험 절차
L-Cysteine (60.4 g, 0.50 mmol) and ethyl glyoxylate (polymer, 47% toluene solution, 50.9 g, 0.234 mol) were added to water (150 ml), and the mixture was stirred at room temperature for 50 hours. The obtained solution was concentrated under reduced pressure, and the precipitated solid was collected by filtration. The obtained white solid (about 40 g) was suspended in water (100 ml), and the suspension was stirred for 16 hours at slurry state. The white crystals were collected by filtration, and dried under reduced pressure to give thiazolidine-2,4-dicarboxylic acid 2-ethyl ester as a white solid (30.08 g).
후처리
- concentrationThe obtained solution was concentrated under reduced pressure
- filtrationthe precipitated solid was collected by filtration
- stirringthe suspension was stirred for 16 hours at slurry state
- filtrationThe white crystals were collected by filtration
- customdried under reduced pressure
출처 및 근거
- ORD 기록
- ord-12434506e2874cdbb5e2421ef6840927
- 출처 데이터셋
- uspto-grants-2015_12
- 특허 번호
- US09212154B2
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