(2S)-1-(benzyloxy)propan-2-ol → (6S)-4,6-Dimethyl-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-3-amine

HRID 1503475노트

반응식

HRID 1503475 반응식
[CH3:1][CH:2]1[C:7]2=[C:8]([NH2:11])[CH:9]=[N:10][N:6]2[CH2:5][C@@H:4]([CH3:12])[O:3]1.C(OC[C@@H](O)C)C1C=CC=CC=1>>[CH3:1][CH:2]1[C:7]2=[C:8]([NH2:11])[CH:9]=[N:10][N:6]2[CH2:5][C@H:4]([CH3:12])[O:3]1

참가 물질

3

반응물 2

HCID 13197475(2S)-1-(benzyloxy)propan-2-olHCID 90010685(6R)-4,6-dimethyl-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-3-amine

생성물 1

HCID 90010546(6S)-4,6-Dimethyl-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-3-amine

실험 절차

(6S)-4,6-Dimethyl-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-3-amine was prepared in a manner analogous to that of (6R)-4,6-dimethyl-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazin-3-amine, starting from (2S)-1-benzyloxypropan-2-ol.

출처 및 근거

ORD 기록
ord-c40ccf0ac70f4e12929820bf6e3bb424
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09212186B2

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