Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → Ethyl 2-(4-formylphenylamino)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone | HCID 6775 | — |
| 반응물 | Glycine, N-(4-methylphenyl)-, ethyl ester | HCID 13263396 | — |
| 용매 | Methanol--water (1/1) | HCID 22242641 | — |
| 생성물 | Ethyl 2-(4-formylphenylamino)acetate | HCID 11579360 | 25.1% |
반응 단계
To a solution of ethyl 2-(p-tolylamino)acetate (1.69 mmol) in methanol/water (20 ml/20 ml) was added the 2,3 dichloro-5,6-dicyanobenzoquinone (2.87 mmol) and the mixture was stirred for 4 hours at room temperature. The residue was chromatographed on a silica gel column (dichloromethane/ethyl acetate 8/2 as eluent) to give 88 mg of ethyl 2-(4-formylphenylamino)acetate. (yield 25%). MS (ESI): m/z 208.0 [M+H]+
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09212196B2 |
| 출처 데이터셋 | uspto-grants-2015_12 |
| ORD ID | ord-2e1bb873d548472f8c07a4805fcfef5d |
| 출처 메모 | uspto-grants-2015_12 |