Methyl trans-4-(4-chlorophenyl)cyclohexanecarboxylate → 3-(4-(4-Chlorophenyl)cyclohexyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole

HRID 1506376노트

반응식

HRID 1506376 반응식
FC1C=CC(C2(CCC3O[N:19]=[C:18]4[C:21]5[C:26]([CH2:27][CH2:28][C:17]=34)=[CH:25][C:24]([CH:29]=[CH2:30])=[CH:23][CH:22]=5)CCCCC2)=CC=1.[Cl:31][C:32]1[CH:37]=[CH:36][C:35]([CH:38]2[CH2:43][CH2:42][CH:41]([C:44]([O:46]C)=O)[CH2:40][CH2:39]2)=[CH:34][CH:33]=1>>[Cl:31][C:32]1[CH:33]=[CH:34][C:35]([CH:38]2[CH2:39][CH2:40][CH:41]([C:44]3[O:46][N:19]=[C:18]4[C:21]5[C:26]([CH2:27][CH2:28][C:17]=34)=[CH:25][C:24]([CH:29]=[CH2:30])=[CH:23][CH:22]=5)[CH2:42][CH2:43]2)=[CH:36][CH:37]=1

참가 물질

3

반응물 2

HCID 14794634Methyl trans-4-(4-chlorophenyl)cyclohexanecarboxylateHCID 671711303-(2-(1-(4-Fluorophenyl)cyclohexyl)ethyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole

생성물 1

HCID 671689533-(4-(4-Chlorophenyl)cyclohexyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole

실험 절차

This compound was prepared according to the general procedure described for Preparation 26A, employing methyl 4-(4-chlorophenyl)cyclohexanecarboxylate as the starting material. LC/MS M+1=390.3.

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-54877cb20523477f86fd3750a2ecabc9
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09216972B2

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