Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Aza-6,9-dichloro-2-methoxyacridine → 7-Chloro-2-methoxy-N-(2-(4-methylpiperazin-1-yl)ethyl)benzo[b][1,5]naphthyridin-10-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Aza-6,9-dichloro-2-methoxyacridine | HCID 23107 | — |
| 반응물 | 4-Methylpiperazine-1-ethylamine | HCID 70284 | — |
| 생성물 | 7-Chloro-2-methoxy-N-(2-(4-methylpiperazin-1-yl)ethyl)benzo[b][1,5]naphthyridin-10-amine | HCID 71006631 | — |
반응 단계
Following the general procedure of Example 1 and making non-critical variations but using 7,10-dichloro-2-methoxypyrido[3,2-b]quinoline and 2-(4-methylpiperazin-1-yl)ethanamine, the title compound was obtained; MS (Found M+1=386). 1H NMR (DMSO-d6, 400 Hz): 8.43-8.41 (d, 1H, J=9.2 Hz), 8.12-8.10 (d, 1H, J=9.2 Hz), 7.87 (b, 1H), 7.2 (s, 1H), 7.2.9-7.27 (d, 1H, J=9.2 Hz) 7.25-7.24 (d, 1H, J=9.2 Hz), 4.10 (m, 2H), 4.06 (s, 3H), 2.70-2.68 (m, 2H), 2.33 (b, 8H), 2.14 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09221760B2 |
| 출처 데이터셋 | uspto-grants-2015_12 |
| ORD ID | ord-06680b69475d4b2ba4696a09cbd34eba |
| 출처 메모 | uspto-grants-2015_12 |