Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Aza-6,9-dichloro-2-methoxyacridine → 7-chloro-N-(1-ethylpiperidin-4-yl)-2-methoxybenzo[b][1,5]naphthyridin-10-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Aza-6,9-dichloro-2-methoxyacridine | HCID 23107 | — |
| 반응물 | 1-Ethylpiperidin-4-amine | HCID 3734990 | — |
| 생성물 | 7-chloro-N-(1-ethylpiperidin-4-yl)-2-methoxybenzo[b][1,5]naphthyridin-10-amine | HCID 70984302 | — |
반응 단계
Following the general procedure of Example 1 and making non-critical variations but using 7,10-dichloro-2-methoxypyrido[3,2-b]quinoline and 1-ethylpiperidin-4-amine, the title compound was obtained; MS (Found M+1=371). 1H NMR (DMSO-d6, 400 Hz): 8.43-8.42 (d, 1H, J=9.2 Hz), 8.11-8.10 (d, 1H, J=9.2 Hz), 7.84 (s, 1H), 7.37-7.35 (d, 1H, J=9.2 Hz) 7.25-7.23 (d, 1H, J=9.2 Hz), 6.95 (b, 1H), 4.98 (b, 1H), 4.00 (s, 3H), 2.85 (b, 2H), 2.30 (b, 2H), 2.02-1.99 (m 4H), 1.00-1.97 (t, 3H, J=7.2 Hz).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09221760B2 |
| 출처 데이터셋 | uspto-grants-2015_12 |
| ORD ID | ord-a36ecb26d6c14a059050c07cfd40e693 |
| 출처 메모 | uspto-grants-2015_12 |