4-Fluorobenzenesulfonyl chloride → Ethyl 2-(4-fluorobenzenesulphonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate

HRID 1506898노트

반응식

HRID 1506898 반응식
[C:1]1([S:7]([NH:10][C:11]2[S:15][C:14]3[CH2:16][CH2:17][CH2:18][CH2:19][C:13]=3[C:12]=2[C:20]([O:22][CH2:23][CH3:24])=[O:21])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.NC1SC2CCCCC=2C=1C(OCC)=O.[F:40]C1C=CC(S(Cl)(=O)=O)=CC=1>>[F:40][C:4]1[CH:3]=[CH:2][C:1]([S:7]([NH:10][C:11]2[S:15][C:14]3[CH2:16][CH2:17][CH2:18][CH2:19][C:13]=3[C:12]=2[C:20]([O:22][CH2:23][CH3:24])=[O:21])(=[O:9])=[O:8])=[CH:6][CH:5]=1

참가 물질

4

반응물 3

HCID 95884-Fluorobenzenesulfonyl chlorideHCID 78262Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylateHCID 391240Ethyl 2-(benzenesulfonamido)-4,5,6,7-tetrahydrobenzothiophene-3-carboxylate

생성물 1

HCID 68278868Ethyl 2-(4-fluorobenzenesulphonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate

실험 절차

Prepared by proceeding in a similar manner to Intermediate 1, starting from ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate and 4-fluorobenzene-sulphonyl chloride

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-eb36245f711b4114b673f6ca415d2bd9
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09221787B2

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