Ethyl 2-formylpyridine-4-carboxylate → HCID 90374998, 화합물

반응식

[CH:1]([C:3]1[CH:8]=[C:7]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:6]=[CH:5][N:4]=1)=O.[CH3:14][N:15]([CH2:17][CH:18]1[CH2:23][CH2:22][CH:21]([CH2:24][NH2:25])[CH2:20][CH2:19]1)[CH3:16]>>[CH3:16][N:15]([CH2:17][CH:18]1[CH2:23][CH2:22][CH:21]([CH2:24][NH:25][CH2:1][C:3]2[CH:8]=[C:7]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:6]=[CH:5][N:4]=2)[CH2:20][CH2:19]1)[CH3:14]

참가 물질

반응물 2

HCID 19600808Ethyl 2-formylpyridine-4-carboxylate

HCID 21843884HCID 21843884, 화합물

생성물 1

HCID 90374998HCID 90374998, 화합물

실험 절차

By General Procedure A from ethyl 2-formylpyridine-4-carboxylate and {4-[(dimethylamino)methyl]cyclohexyl}methanamine. Aqueous work up gave the title compound as a yellow oil. Used without further purification. 1H NMR (300 MHz, chloroform-d): δ ppm 8.41 (d, 1H), 8.04 (s, 1H), 7.49 (d, 1H), 4.04 (q, 2H), 3.39 (s, 2H), 2.46 (m, 4H), 2.38 (d, 6H), 1.60 (m, 4H), 1.34 (t, 3H), 1.03 (m, 2H), 0.68 (m, 4H).

출처 및 근거

ORD 기록: ord-a32ef5bcf602421a8c13474aa62f62c3
출처 데이터셋: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09221801B2

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