2,6-Dimethylpyrimidine-4-carboxylic acid → HCID 73426447, 화합물

반응식

[NH2:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH3:14])([CH3:13])[C:7](=[O:12])[N:8]2[CH3:11])=[CH:4][CH:3]=1.[CH3:15][C:16]1[N:21]=[C:20]([C:22](O)=[O:23])[CH:19]=[C:18]([CH3:25])[N:17]=1>>[CH3:15][C:16]1[N:21]=[C:20]([C:22]([NH:1][C:2]2[CH:10]=[C:9]3[C:5]([C:6]([CH3:14])([CH3:13])[C:7](=[O:12])[N:8]3[CH3:11])=[CH:4][CH:3]=2)=[O:23])[CH:19]=[C:18]([CH3:25])[N:17]=1

참가 물질

반응물 2

HCID 176047652,6-Dimethylpyrimidine-4-carboxylic acid

HCID 529112486-Amino-1,3,3-trimethyl-1,3-dihydro-2H-indol-2-one

생성물 1

HCID 73426447HCID 73426447, 화합물

실험 절차

Prepared in analogy to example 1b from 6-amino-1,3,3-trimethylindolin-2-one and 2,6-dimethylpyrimidine-4-carboxylic acid. The title compound was obtained as white foam.

출처 및 근거

ORD 기록: ord-f0042b2c46f8464f83c63c842e6be832
출처 데이터셋: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09221816B2

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