3-Fluoropyridine-4-carboxylic acid → N-(1-(3-Cyclopropoxypropyl)-3,3-dimethyl-2-oxoindolin-6-yl)-3-fluoroisonicotinamide
반응식
[NH2:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH3:20])([CH3:19])[C:7](=[O:18])[N:8]2[CH2:11][CH2:12][CH2:13][O:14][CH:15]2[CH2:17][CH2:16]2)=[CH:4][CH:3]=1.[F:21][C:22]1[CH:30]=[N:29][CH:28]=[CH:27][C:23]=1[C:24](O)=[O:25]>>[CH:15]1([O:14][CH2:13][CH2:12][CH2:11][N:8]2[C:9]3[C:5](=[CH:4][CH:3]=[C:2]([NH:1][C:24](=[O:25])[C:23]4[CH:27]=[CH:28][N:29]=[CH:30][C:22]=4[F:21])[CH:10]=3)[C:6]([CH3:20])([CH3:19])[C:7]2=[O:18])[CH2:16][CH2:17]1참가 물질
3
실험 절차
Prepared in analogy to example 26 from 6-amino-1-(3-cyclopropoxypropyl)-3,3-dimethylindolin-2-one and 3-fluoroisonicotinic acid. The title compound was obtained as yellow oil.
출처 및 근거
- ORD 기록
- ord-314e81ee51c64b419bfe97a4b0a2a8d9
- 출처 데이터셋
- uspto-grants-2015_12