Furo[2,3-C]pyridin-3(2H)-one → 5-chlorofuro[2,3-c]pyridin-3(2H)-one

반응식

O1C2=CN=CC=C2C(=O)C1.C(OC([C:16]1[O:25][C:19]2=[CH:20][N:21]=[C:22]([Cl:24])[CH:23]=[C:18]2[C:17]=1[OH:26])=O)C>>[Cl:24][C:22]1[CH:23]=[C:18]2[C:17](=[O:26])[CH2:16][O:25][C:19]2=[CH:20][N:21]=1

참가 물질

반응물 2

HCID 14199080Furo[2,3-C]pyridin-3(2H)-one

HCID 867219175-Chloro-3-hydroxyfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester

생성물 1

HCID 867219185-chlorofuro[2,3-c]pyridin-3(2H)-one

실험 절차

This compound was prepared using a method analogous to that of furo[2,3-c]pyridin-3(2H)-one (A.2.4.3), 5-chloro-3-hydroxyfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester replacing 3-hydroxyfuro[2,3-c]pyridine-2-carboxylic acid ethyl ester;

후처리

customThis compound was prepared

출처 및 근거

ORD 기록: ord-ca320305917a46b8ab9f0630ed0c04c7
출처 데이터셋: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09221832B2

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