Ethyl 2-chloro-6-methylnicotinate → 3-Hydroxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

HRID 1508231노트

반응식

HRID 1508231 반응식
[CH2:1]([O:3][C:4]([C:6]1[O:14][C:9]2[N:10]=N[CH:12]=[CH:13][C:8]=2[C:7]=1[OH:15])=[O:5])[CH3:2].[CH2:16](OC(=O)C1C=CC(C)=NC=1Cl)[CH3:17]>>[CH2:1]([O:3][C:4]([C:6]1[O:14][C:9]2=[N:10][C:16]([CH3:17])=[CH:12][CH:13]=[C:8]2[C:7]=1[OH:15])=[O:5])[CH3:2]

참가 물질

3

반응물 2

HCID 15574421Ethyl 2-chloro-6-methylnicotinateHCID 71239586HCID 71239586, 화합물

생성물 1

HCID 712395013-Hydroxy-6-methylfuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

실험 절차

This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 2-chloro-6-methylnicotinic acid ethyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester;

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-124fa2cd4df04164a5f4f93931091147
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09221832B2

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