Methyl 2,6-dichloropyridine-3-carboxylate → 3-Hydroxy-6-chlorofuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

HRID 1508235노트

반응식

HRID 1508235 반응식
[CH2:1]([O:3][C:4]([C:6]1[O:14][C:9]2[N:10]=N[CH:12]=[CH:13][C:8]=2[C:7]=1[OH:15])=[O:5])[CH3:2].COC(=O)C1C=C[C:22]([Cl:25])=NC=1Cl>>[CH2:1]([O:3][C:4]([C:6]1[O:14][C:9]2=[N:10][C:22]([Cl:25])=[CH:12][CH:13]=[C:8]2[C:7]=1[OH:15])=[O:5])[CH3:2]

참가 물질

3

반응물 2

HCID 11106516Methyl 2,6-dichloropyridine-3-carboxylateHCID 71239586HCID 71239586, 화합물

생성물 1

HCID 867219313-Hydroxy-6-chlorofuro[2,3-b]pyridine-2-carboxylic acid ethyl ester

실험 절차

This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 2,6-dichloronicotinic acid methyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester;

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-397777b148e846758fcb874807565779
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09221832B2

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