2-Fluorobenzenesulphonyl chloride → 8-bromo-4-(2-fluorobenzenesulfonyl)-2,2-dimethyl-3,4-dihydro-2H-benzo[1,4]oxazine

HRID 150909

반응식

HRID 150909 반응식
[Br:14][c:15]1[c:16]2[c:24]([cH:25][cH:26][cH:27]1)[NH:23][C:21](=[O:22])[C:18]([CH3:19])([CH3:20])[O:17]2.[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[O:10][C:9]([CH3:12])([CH3:13])[CH2:8][NH:7]2.[F:37][c:38]1[c:39]([S:44](=[O:45])(=[O:46])[Cl:47])[cH:40][cH:41][cH:42][cH:43]1.[NH2:28][c:29]1[cH:30][cH:31][cH:32][c:33]([Br:34])[c:35]1[OH:36]>>[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[O:10][C:9]([CH3:12])([CH3:13])[CH2:8][N:7]2[S:44]([c:39]1[c:38]([F:37])[cH:43][cH:42][cH:41][cH:40]1)(=[O:45])=[O:46]

참가 물질

5

반응물 4

HCID 1377612-Fluorobenzenesulphonyl chlorideHCID 155315062-Amino-6-bromophenolHCID 184491008-bromo-2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazineHCID 218735118-Bromo-2,2-dimethyl-2H-1,4-benzoxazin-3(4H)-one

생성물 1

HCID 225572828-bromo-4-(2-fluorobenzenesulfonyl)-2,2-dimethyl-3,4-dihydro-2H-benzo[1,4]oxazine

출처 및 근거

ORD 기록
ord-72d47f66979b401a961d827eb141bbf8
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

연결된 노트

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