2,6-Difluorobenzenesulfonyl chloride → N-{3-[5-(2-Chloropyrimidin-4-yl)-2-(morpholin-4-yl)-1,3-thiazol-4-yl]-2-methoxyphenyl}-2,6-difluorobenzene-1-sulfonamide

HRID 150943

반응식

HRID 150943 반응식
[Cl:1][c:2]1[n:3][c:4](-[c:5]2[s:6][c:7]([CH:8]([CH3:9])[CH3:10])[n:11][c:12]2-[c:13]2[cH:14][c:15]([NH:16][S:23](=[O:24])(=[O:25])[c:26]3[c:27]([F:33])[cH:28][cH:29][cH:30][c:31]3[F:32])[cH:17][cH:18][cH:19]2)[cH:20][cH:21][n:22]1.[Cl:34][c:35]1[n:36][cH:37][cH:38][c:39](-[c:41]2[c:42](-[c:52]3[c:53]([O:59][CH3:60])[c:54]([NH2:55])[cH:56][cH:57][cH:58]3)[n:43][c:44]([N:46]3[CH2:47][CH2:48][O:49][CH2:50][CH2:51]3)[s:45]2)[n:40]1.[F:61][c:62]1[cH:63][cH:64][cH:65][c:66]([F:67])[c:68]1[S:69]([Cl:70])(=[O:71])=[O:72]>>[S:23](=[O:24])(=[O:25])([c:26]1[c:27]([F:33])[cH:28][cH:29][cH:30][c:31]1[F:32])[NH:55][c:54]1[c:53]([O:59][CH3:60])[c:52](-[c:42]2[c:41](-[c:39]3[cH:38][cH:37][n:36][c:35]([Cl:34])[n:40]3)[s:45][c:44]([N:46]3[CH2:47][CH2:48][O:49][CH2:50][CH2:51]3)[n:43]2)[cH:58][cH:57][cH:56]1

참가 물질

4

반응물 3

HCID 27342712,6-Difluorobenzenesulfonyl chlorideHCID 579897953-(5-(2-Chloropyrimidin-4-yl)-2-morpholinothiazol-4-yl)-2-methoxyanilineHCID 57990030N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]phenyl}-2,6-difluorobenzenesulfonamide

생성물 1

HCID 53487989N-{3-[5-(2-Chloropyrimidin-4-yl)-2-(morpholin-4-yl)-1,3-thiazol-4-yl]-2-methoxyphenyl}-2,6-difluorobenzene-1-sulfonamide

출처 및 근거

ORD 기록
ord-c2c79e43554945148e775e1da73f8cad
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

연결된 노트

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