2-Amino-1,3-thiazole-5-carbaldehyde → N-(5-Formylthiazol-2-yl)-3-isopropoxy-5-phenoxybenzamide
반응식
[CH:1]([C:3]1[S:7][C:6]([NH2:8])=[N:5][CH:4]=1)=[O:2].[CH:9]([O:12][C:13]1[CH:14]=[C:15]([CH:19]=[C:20]([O:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:21]=1)[C:16](O)=[O:17])([CH3:11])[CH3:10]>>[CH:1]([C:3]1[S:7][C:6]([NH:8][C:16](=[O:17])[C:15]2[CH:19]=[C:20]([O:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH:21]=[C:13]([O:12][CH:9]([CH3:10])[CH3:11])[CH:14]=2)=[N:5][CH:4]=1)=[O:2]참가 물질
3
실험 절차
N-(5-Formylthiazol-2-yl)-3-isopropoxy-5-phenoxybenzamide (460 mg) was prepared in 41% yield from 5-formyl-2-aminothiazole (600 mg, 4.7 mmol) and 3-isopropyloxy-5-phenoxybenzoic acid (800 mg, 2.95 mmol) following general synthetic description A.
출처 및 근거
- ORD 기록
- ord-e3f8a60c79b04077865c1f82c8c6bda0
- 출처 데이터셋
- uspto-grants-2012_07