3-Methyl-N-{[(pent-4-en-1-yl)oxy]carbonyl}-L-valine → (2S)-(1-methylcyclohexyl) {[(pent-4-en-1-yloxy)carbonyl]amino}acetic acid

HRID 1511580

반응식

HRID 1511580 반응식
[CH3:1][C:2]([CH3:17])([CH3:16])[C@@H:3]([C:13]([OH:15])=[O:14])[NH:4][C:5]([O:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH2:12])=[O:6].Cl.N[C@@H:20]([C:24]1(C)CCCCC1)[C:21](O)=O>>[CH3:1][C:2]1([C@H:3]([NH:4][C:5]([O:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH2:12])=[O:6])[C:13]([OH:15])=[O:14])[CH2:17][CH2:24][CH2:20][CH2:21][CH2:16]1

참가 물질

3

반응물 2

HCID 453799283-Methyl-N-{[(pent-4-en-1-yl)oxy]carbonyl}-L-valineHCID 57462912(S)-2-Amino-2-(1-methylcyclohexyl)acetic acid hydrochloride

생성물 1

HCID 45378511(2S)-(1-methylcyclohexyl) {[(pent-4-en-1-yloxy)carbonyl]amino}acetic acid

실험 절차

(2S)-(1-methylcyclohexyl) {[(pent-4-en-1-yloxy)carbonyl]amino}acetic acid was prepared according to the procedure for 3-methyl-N-[(pent-4-enyloxy)carbonyl]-L-valine by using (2S)-amino(1-methylcyclohexyl)acetic acid-HCl instead of t-butylglycine. LRMS (ESI) m/z 347.3 [(M+Na+CH3CN)+; calcd for C17H28N2NaO4: 347.2].

출처 및 근거

ORD 기록
ord-40b8aebf6d084ccd9a514e4a1a1c5c61
출처 데이터셋
uspto-grants-2012_07
특허 번호
US08216999B2

연결된 노트

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