1,2-Dichloro-4-fluorobenzene → HCID 68411177, 화합물

반응식

[CH3:1][C:2]1[O:12][C:5]2[CH2:6][N:7]([CH3:11])[CH2:8][CH:9]([OH:10])[C:4]=2[CH:3]=1.[Cl:13][C:14]1[CH:15]=[C:16](F)[CH:17]=[CH:18][C:19]=1[Cl:20]>>[ClH:13].[Cl:13][C:14]1[CH:15]=[C:16]([O:10][CH:9]2[CH2:8][N:7]([CH3:11])[CH2:6][C:5]3[O:12][C:2]([CH3:1])=[CH:3][C:4]2=3)[CH:17]=[CH:18][C:19]=1[Cl:20]

참가 물질

반응물 2

HCID 740281,2-Dichloro-4-fluorobenzene

HCID 13365215HCID 13365215, 화합물

생성물 1

HCID 68411177HCID 68411177, 화합물

실험 절차

The same method as in Example 3 was conducted using 2,6-dimethyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 2) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3,4-dichloro-1-fluorobenzene instead of 1,3-difluorobenzene to give the objective compound.

후처리

customto give the objective compound

출처 및 근거

ORD 기록: ord-ea328ded41cd4efa9f4f82ad6525f0ab
출처 데이터셋: uspto-grants-2012_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08217031B2

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