HCID 67144710, 화합물 → HCID 68411024, 화합물
반응식
[CH3:1][N:2]1[CH2:8][CH2:7][CH:6]([OH:9])[C:5]2[CH:10]=[CH:11][O:12][C:4]=2[CH2:3]1.[CH3:13][NH:14][C:15]([C:17]1[C:18]([Cl:24])=[C:19](F)[CH:20]=[CH:21][CH:22]=1)=[O:16]>>[ClH:24].[CH3:13][NH:14][C:15]([C:17]1[C:18]([Cl:24])=[C:19]([O:9][CH:6]2[CH2:7][CH2:8][N:2]([CH3:1])[CH2:3][C:4]3[O:12][CH:11]=[CH:10][C:5]2=3)[CH:20]=[CH:21][CH:22]=1)=[O:16]참가 물질
3
실험 절차
The same method as in Example 3 was conducted using 7-methyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol (Reference Example 19) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3-methylcarbamoyl-2-chloro-1-fluorobenzene instead of 1,3-difluorobenzene to give the objective compound.
후처리
- customto give the objective compound
출처 및 근거
- ORD 기록
- ord-fde564297435429c8a73ae673d74e7b3
- 출처 데이터셋
- uspto-grants-2012_07