Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chloro-4-fluorobenzamide → 7-(4-Carbamoyl-2-chlorophenyloxy)-5-ethyl-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chloro-4-fluorobenzamide | HCID 2736520 | — |
| 반응물 | 5-Ethyl-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol | HCID 68412460 | — |
| 생성물 | 7-(4-Carbamoyl-2-chlorophenyloxy)-5-ethyl-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine | HCID 68412710 | — |
반응 단계
The same method as in Example 1 was conducted using 5-ethyl-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol (Reference Example 32) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 4-carbamoyl-2-chloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08217031B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-a1c687e99a154769a98260c25d05d06e |
| 출처 메모 | uspto-grants-2012_07 |