1-Bromo-2-fluorobenzene → HCID 68411839, 화합물

HRID 1511775노트

반응식

HRID 1511775 반응식
[CH2:1]([N:3]1[CH2:8][CH:7]([OH:9])[C:6]2[O:10][CH:11]=[CH:12][C:5]=2[CH2:4]1)[CH3:2].[Br:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1F>>[Br:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[O:9][CH:7]1[CH2:8][N:3]([CH2:1][CH3:2])[CH2:4][C:5]2[CH:12]=[CH:11][O:10][C:6]1=2

참가 물질

3

반응물 2

HCID 612591-Bromo-2-fluorobenzeneHCID 684101205-Ethyl-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-7-ol

생성물 1

HCID 68411839HCID 68411839, 화합물

실험 절차

The same method as in Example 1 was conducted using 5-ethyl-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-7-ol (Reference Example 34) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2-bromo-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.

후처리

  1. customto give the objective compound

출처 및 근거

ORD 기록
ord-d3241ae6b64e496e84d02f2711c05954
출처 데이터셋
uspto-grants-2012_07
특허 번호
US08217031B2

반응 노트

불러오는 중…