1-Cyano-4-fluoronaphthalene → HCID 68409676, 화합물

HRID 1511777노트

반응식

HRID 1511777 반응식
[CH2:1]([N:3]1[CH2:8][CH:7]([OH:9])[C:6]2[O:10][CH:11]=[CH:12][C:5]=2[CH2:4]1)[CH3:2].[C:13]([C:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18](F)=[CH:17][CH:16]=1)#[N:14]>>[C:13]([C:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18]([O:9][CH:7]2[CH2:8][N:3]([CH2:1][CH3:2])[CH2:4][C:5]3[CH:12]=[CH:11][O:10][C:6]2=3)=[CH:17][CH:16]=1)#[N:14]

참가 물질

3

반응물 2

HCID 27367341-Cyano-4-fluoronaphthaleneHCID 684101205-Ethyl-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-7-ol

생성물 1

HCID 68409676HCID 68409676, 화합물

실험 절차

The same method as in Example 1 was conducted using 5-ethyl-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-7-ol (Reference Example 34) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 4-cyano-1-fluoronaphthalene instead of 1-fluoronaphthalene to give the objective compound.

후처리

  1. customto give the objective compound

출처 및 근거

ORD 기록
ord-497ad5b15b9a4c408fcd3d9ee53002cc
출처 데이터셋
uspto-grants-2012_07
특허 번호
US08217031B2

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