HCID 44549262, 화합물 → HCID 53404692, 화합물

HRID 1512980노트

반응식

HRID 1512980 반응식
[CH3:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][N:5]=[C:4]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:3]=1>C(O)C.[C].[Pd]>[NH2:8][C:7]1[C:2]([CH3:1])=[CH:3][C:4]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[N:5][CH:6]=1

참가 물질

4

반응물 1

HCID 44549262HCID 44549262, 화합물

생성물 1

HCID 53404692HCID 53404692, 화합물수율 98.9%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

A mixture of ethyl 4-methyl-5-nitropyridine-2-carboxylate (3.23 g) and 10% palladium-carbon powder (0.65 g) in ethanol (50 mL) was stirred at room temperature under a hydrogen atmosphere overnight. The insoluble material was removed by filtration, and the filtrate was concentrated under reduced pressure to give the title compound (2.74 g).

후처리

  1. customThe insoluble material was removed by filtration
  2. concentrationthe filtrate was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-affccc2327f74309bef80e98dd2f71e6
출처 데이터셋
uspto-grants-2012_07
특허 번호
US08217069B2

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