Chloroacetyl chloride → 4-chloro-N'-(2-chloroacetyl)benzohydrazide

HRID 1513

반응식

HRID 1513 반응식
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.[Cl:12][CH2:13][C:14](Cl)=[O:15]>O1CCOCC1>[Cl:12][CH2:13][C:14]([NH:9][NH:8][C:6](=[O:7])[C:5]1[CH:10]=[CH:11][C:2]([Cl:1])=[CH:3][CH:4]=1)=[O:15]

참가 물질

4

반응물 2

HCID 6577Chloroacetyl chlorideHCID 108164-Chlorobenzohydrazide

생성물 1

HCID 5212924-chloro-N'-(2-chloroacetyl)benzohydrazide

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

To a solution of p-chlorobenzoic hydrazide (11.2 g) in dioxane (100 ml) was added chloroacetyl chloride (6 ml). The resulting mixture was refluxed for three hours cooled to room temperature and filtered. The resulting solid was washed with ethyl ether and dried to yield N'-chloroacetyl-4-chlorobenzoic hydrazide as white solid.

후처리

  1. temperatureThe resulting mixture was refluxed for three hours
  2. filtrationfiltered
  3. washThe resulting solid was washed with ethyl ether
  4. customdried

출처 및 근거

ORD 기록
ord-5b77163772334a28b4e039cda3410b19
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05726162

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