Tert-butyl 2-(3-methoxyquinolin-6-yl)acetate → 2-(3-Methoxyquinolin-6-yl)acetic acid hydrochloride

반응식

[CH3:1][O:2][C:3]1[CH:4]=[N:5][C:6]2[C:11]([CH:12]=1)=[CH:10][C:9]([CH2:13][C:14]([O:16]C(C)(C)C)=[O:15])=[CH:8][CH:7]=2.[ClH:21].COC1C=NC2C(C=1)=CC(C(C)C(O)=O)=CC=2>>[ClH:21].[CH3:1][O:2][C:3]1[CH:4]=[N:5][C:6]2[C:11]([CH:12]=1)=[CH:10][C:9]([CH2:13][C:14]([OH:16])=[O:15])=[CH:8][CH:7]=2

참가 물질

반응물 2

HCID 59843087Tert-butyl 2-(3-methoxyquinolin-6-yl)acetate

HCID 675035432-(3-Methoxyquinolin-6-yl)propanoic acid hydrochloride

생성물 1

HCID 675033532-(3-Methoxyquinolin-6-yl)acetic acid hydrochloride

실험 절차

tert-Butyl 2-(3-methoxyquinolin-6-yl)acetate was saponified in a method similar to 2-(3-methoxyquinolin-6-yl)propanoic acid hydrochloride.

출처 및 근거

ORD 기록: ord-0f128061f93a408ea227b2ea9ede4ad4
출처 데이터셋: uspto-grants-2012_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08217177B2

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