Water → HCID 58320692, 화합물

HRID 1515369노트

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HRID 1515369 반응식
[CH3:1][CH2:2][C:3]([C:5](Cl)=[O:6])=[O:4].C=[C:9]1[O:13][CH2:12]C[O:10]1.N1[CH:19]=[CH:18]C=CC=1.[OH2:20]>C(Cl)Cl>[O:13]1[CH2:12]/[C:1](=[CH:2]\[C:3](=[O:4])[C:5]([O:6][CH2:18][CH3:19])=[O:20])/[O:10][CH2:9]1

참가 물질

6

반응물 4

HCID 962WaterHCID 1049PyridineHCID 11007880Butanoyl chloride, 2-oxo-HCID 117684952-Methylene-1,3-dioxolane

생성물 1

HCID 58320692HCID 58320692, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

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온도
5 °C

실험 절차

The solution of ethyloxalyl chloride (10.3 g, 75.5 mmol) in CH2Cl2 (10 mL) was added at 0° C. to the solution of methylene dioxolane (6.5 g, 75.5 mmol) and pyridine (6.3 g, 80 mmol) in CH2Cl (80 mL). The reaction mixture was stirred for 10 hours at 5° C. and diluted with 200 ml of water. The product was extracted with 200 ml of hexane, the solution of hexane was dried with MgSO4 and concentrated by evaporation. This gave 11.9 g (85%) of the product, b.p. 106-110° C./0.5 mmHg.

후처리

  1. extractionThe product was extracted with 200 ml of hexane
  2. dry with materialthe solution of hexane was dried with MgSO4
  3. concentrationconcentrated by evaporation

출처 및 근거

ORD 기록
ord-a5537c31416c4e8abd352e75baddf41d
출처 데이터셋
uspto-grants-2012_07
특허 번호
US08222435B2

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