N,6-Dimethyl-5-nitropyridin-2-amine → HCID 55285663, 화합물
반응식
[CH3:1][NH:2][C:3]1[N:8]=[C:7]([CH3:9])[C:6]([N+:10]([O-])=O)=[CH:5][CH:4]=1.[H][H]>CO.[Pd]>[CH3:1][NH:2][C:3]1[N:8]=[C:7]([CH3:9])[C:6]([NH2:10])=[CH:5][CH:4]=1참가 물질
5
실험 절차
A suspension of 0.4 g (2.39 mmol) of 6-methylamino-2-methyl-3-nitropyridine (Prace Naukowe Akedimii Ekonomicznej imienia Oskara Langego we Wroclawiu (1988), 435, 119-28) and 0.1 g of 10% palladium-on-charcoal in 50 ml of methanol is stirred at 20° C. for 6 hours under 4 atmospheres of hydrogen. The reaction mixture is subsequently filtered through a celite plug and then concentrated under reduced pressure. 0.33 g of the expected product is thus isolated in the form of an oil which will be used as is in the continuation of the synthesis.
후처리
- filtrationThe reaction mixture is subsequently filtered through a celite plug
- concentrationconcentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-b642c057e7aa4701a3d5057d2191e32f
- 출처 데이터셋
- uspto-grants-2012_07
- 특허 번호
- US08227489B2
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