돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1518생성일: 2026년 10월 25일

Potassium Carbonate → (S)-Glycidyl-2-benzyloxyphenol

https://huagongshe.com/reaction/1518

반응식

참여 물질

역할이름HCID투입량
반응물Potassium CarbonateHCID 11430—
반응물2-BenzyloxyphenolHCID 80459—
반응물Benzenesulfonic acid, 3-nitro-, (2S)-2-oxiranylmethyl esterHCID 146490—
용매AcetoneHCID 180—
생성물(S)-Glycidyl-2-benzyloxyphenolHCID 53650482—

반응 단계

A mixture of 2-benzyloxyphenol (900 mg, 4.5 mMol) and potassium carbonate (1.87 g, 13.5 mMol) in acetone (45 ml) was heated under reflux for 15 mins. (S)-Glycidyl-3-nitrobenzenesulphonate (1.0 g, 4.5 mMol) was added and the reaction mixture was heated under reflux for 23 hours. After cooling, the reaction mixture was filtered and the solvent was evaporated. The residue was partitioned between ethyl acetate and water. The organic fractions were combined, washed with water and brine, dried and evaporated to give the title compound as an oil.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05726165
출처 데이터셋uspto-grants-1998_03
ORD IDord-eb63de3fd8b24647933622c8df3a84d0
출처 메모uspto-grants-1998_03