Piperazine → Benzoic acid, 2-bromo-4-(1-piperazinyl)-, methyl ester

HRID 1518793노트

반응식

HRID 1518793 반응식
[NH:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[Br:7][C:8]1[CH:17]=[C:16](F)[CH:15]=[CH:14][C:9]=1[C:10]([O:12][CH3:13])=[O:11]>>[Br:7][C:8]1[CH:17]=[C:16]([N:1]2[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]2)[CH:15]=[CH:14][C:9]=1[C:10]([O:12][CH3:13])=[O:11]

참가 물질

3

반응물 2

HCID 4837PiperazineHCID 7210837Methyl 2-bromo-4-fluorobenzoate

생성물 1

HCID 67227310Benzoic acid, 2-bromo-4-(1-piperazinyl)-, methyl ester

실험 절차

This example was prepared by substituting piperazine for EXAMPLE 1B and methyl 2-bromo-4-fluorobenzoate for EXAMPLE 1C in EXAMPLE 1D.

출처 및 근거

ORD 기록
ord-075fa2bce35d41f7a0fbccb05334ff7a
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09072748B2

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