4-Methoxybenzenethiol → 1-Bromo-3-fluoro-2-(4-methoxy-phenylsulfanyl)-benzene

반응식

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([SH:9])=[CH:5][CH:4]=1.[Br:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[C:12]=1I.BrC1C=CC=C(F)C=1N>>[Br:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[C:12]=1[S:9][C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1

참가 물질

반응물 3

HCID 127654-Methoxybenzenethiol

HCID 27829402-Bromo-6-fluoroaniline

HCID 27831271-Bromo-3-fluoro-2-iodobenzene

생성물 1

HCID 686828891-Bromo-3-fluoro-2-(4-methoxy-phenylsulfanyl)-benzene

실험 절차

Prepared from 4-methoxy-benzenethiol and 1-bromo-3-fluoro-2-iodo-benzene (prepared from 2-bromo-6-fluoro-phenylamine by diazotization according to the general procedure by Tunney and Stille J. Org. Chem. 1987, 52, 748-753).

출처 및 근거

ORD 기록: ord-deecd597bab4449d99508d960324b959
출처 데이터셋: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07732463B2

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