Alanine, ethyl ester, hydrochloride (1:1) → HCID 68444993, 화합물
반응식
[CH3:1][C:2]1[O:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]=1[CH2:13][O:14][C:15]1[CH:23]=[CH:22][C:18]([C:19]([OH:21])=O)=[CH:17][N:16]=1.Cl.[CH2:25]([O:27][C:28](=[O:32])[CH:29]([CH3:31])[NH2:30])[CH3:26]>>[CH2:25]([O:27][C:28](=[O:32])[CH:29]([NH:30][C:19]([C:18]1[CH:17]=[N:16][C:15]([O:14][CH2:13][C:3]2[C:4]([C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=3)=[N:5][O:6][C:2]=2[CH3:1])=[CH:23][CH:22]=1)=[O:21])[CH3:31])[CH3:26]참가 물질
3
실험 절차
As described for example 15, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.32 mmol) was converted, using DL-alanine ethylester hydrochloride instead of 3-methoxypropylamine, to the title compound (23 mg, 17%) which was obtained as a light yellow gum. MS: m/e=410.1 [M+H]+.
출처 및 근거
- ORD 기록
- ord-098187baa25143a9b85bbc45ecd1697e
- 출처 데이터셋
- uspto-grants-2015_07