3-(Morpholin-4-yl)aniline → 4-(2-aminopyrimidin-5-yl)-2-morpholin-4-yl-N-(3-morpholin-4-ylphenyl)-5,6-dihydropyrrolo[2,3-d]pyrimidine-7-carboxamide

HRID 152189

반응식

[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]([CH2:9][c:10]2[cH:11][cH:12][c:13]([O:14][CH3:15])[cH:16][cH:17]2)[c:18]2[n:19][cH:20][c:21](-[c:22]3[c:23]4[c:27]([n:28][c:29]([N:30]5[CH2:31][CH2:32][O:33][CH2:34][CH2:35]5)[n:36]3)[NH:26][CH2:25][CH2:24]4)[cH:37][n:38]2)[cH:39][cH:40]1.[O:41]1[CH2:42][CH2:43][N:44]([c:45]2[cH:46][c:47]([NH2:48])[cH:49][cH:50][cH:51]2)[CH2:52][CH2:53]1.[O:54]1[CH2:55][CH2:56][N:57]([c:60]2[cH:61][c:62]([NH:66][C:67](=[O:68])[N:69]3[CH2:70][CH2:71][c:72]4[c:73]3[n:74][c:75]([N:103]3[CH2:104][CH2:105][O:106][CH2:107][CH2:108]3)[n:76][c:77]4-[c:78]3[cH:79][n:80][c:81]([N:84]([CH2:85][c:86]4[cH:87][cH:88][c:89]([O:90][CH3:91])[cH:92][cH:93]4)[CH2:94][c:95]4[cH:96][cH:97][c:98]([O:99][CH3:100])[cH:101][cH:102]4)[n:82][cH:83]3)[cH:63][cH:64][cH:65]2)[CH2:58][CH2:59]1>>[O:54]1[CH2:55][CH2:56][N:57]([c:60]2[cH:61][c:62]([NH:66][C:67](=[O:68])[N:69]3[CH2:70][CH2:71][c:72]4[c:73]3[n:74][c:75]([N:103]3[CH2:104][CH2:105][O:106][CH2:107][CH2:108]3)[n:76][c:77]4-[c:78]3[cH:79][n:80][c:81]([NH2:84])[n:82][cH:83]3)[cH:63][cH:64][cH:65]2)[CH2:58][CH2:59]1

참가 물질

반응물 3

HCID 8477683-(Morpholin-4-yl)aniline

HCID 45258862Bis-(4-methoxybenzyl)-[5-(2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-yl]-amine

HCID 866401304-{2-[Bis-(4-methoxy-benzyl)-amino]-pyrimidin-5-yl}-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid (3-morpholin-4-yl-phenyl)-amide

생성물 1

HCID 592448384-(2-aminopyrimidin-5-yl)-2-morpholin-4-yl-N-(3-morpholin-4-ylphenyl)-5,6-dihydropyrrolo[2,3-d]pyrimidine-7-carboxamide

출처 및 근거

ORD 기록: ord-f7ea65a41f384dcab66eff7865d7ac92
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

연결된 노트

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