Sodium Azide → (S)-1-azido-3-(3-(2-ethylbutoxy)phenyl)propan-2-ol

HRID 1523152노트

반응식

Cl[CH2:2][C@@H:3]([OH:18])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][CH2:12][CH:13]([CH2:16][CH3:17])[CH2:14][CH3:15])[CH:6]=1.[N-:19]=[N+:20]=[N-:21].[Na+]>>[N:19]([CH2:2][C@@H:3]([OH:18])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][CH2:12][CH:13]([CH2:16][CH3:17])[CH2:14][CH3:15])[CH:6]=1)=[N+:20]=[N-:21]

참가 물질

반응물 2

HCID 33557Sodium Azide

HCID 67317444(S)-1-chloro-3-(3-(2-ethylbutoxy)phenyl)propan-2-ol

생성물 1

HCID 86637616(S)-1-azido-3-(3-(2-ethylbutoxy)phenyl)propan-2-ol

실험 절차

Treatment of (S)-1-chloro-3-(3-(2-ethylbutoxy)phenyl)propan-2-ol with sodium azide following the method used in Example 6 gave (S)-1-azido-3-(3-(2-ethylbutoxy)phenyl)propan-2-ol which was used without further purification.

출처 및 근거

ORD 기록: ord-e8eb39c9593e4b0f9c9ceb887d79edd8
출처 데이터셋: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09079825B2

반응 노트

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