Acetonitrile → HCID 67316482, 화합물

HRID 1523168노트

반응식

HRID 1523168 반응식
[CH3:1][O:2][C:3]1[CH:18]=[CH:17][CH:16]=[CH:15][C:4]=1[CH2:5][O:6][C:7]1[CH:8]=[C:9]([CH:12]=[CH:13][CH:14]=1)[CH:10]=[O:11].[C:19](#[N:21])[CH3:20]>>[CH3:1][O:2][C:3]1[CH:18]=[CH:17][CH:16]=[CH:15][C:4]=1[CH2:5][O:6][C:7]1[CH:8]=[C:9]([CH:10]([OH:11])[CH2:20][C:19]#[N:21])[CH:12]=[CH:13][CH:14]=1

참가 물질

3

반응물 2

HCID 6342AcetonitrileHCID 197446743-[(2-Methoxybenzyl)oxy]benzaldehyde

생성물 1

HCID 67316482HCID 67316482, 화합물

실험 절차

Addition of acetonitrile to 3-(2-methoxybenzyloxy)benzaldehyde gave 3-(3-(2-methoxybenzyloxy)phenyl)-3-hydroxypropanenitrile as yellow oil. Yield (0.88 g, 47%): 1H NMR (400 MHz, CDCl3) δ 7.42-7.46 (m, 1H), 7.27-7.31 (m, 2H), 6.90-7.06 (m, 5H), 5.12 (s, 2H), 5.01 (m, 1H), 3.87 (s, 3H), 2.76-2.82 (m, 2H).

출처 및 근거

ORD 기록
ord-b49db0e828c449c5a4d4294767f90d05
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09079825B2

반응 노트

불러오는 중…