3-[1,2,3]Triazol-2-yl-pyridine-2-carboxylic acid → tert-Butyl 5-(3-(2H-1,2,3-triazol-2-yl)picolinoyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

HRID 1524922

반응식

HRID 1524922 반응식
N1N=C(C2C=CC=CC=2C([N:14]2[CH2:18][CH:17]3[CH2:19][N:20]([C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[CH2:21][CH:16]3[CH2:15]2)=O)NC=1.[N:29]1[N:30]([C:34]2[C:35]([C:40]([OH:42])=O)=[N:36][CH:37]=[CH:38][CH:39]=2)[N:31]=[CH:32][CH:33]=1.N1N=C(C2C=CC=CC=2C(O)=O)NC=1>>[N:31]1[N:30]([C:34]2[C:35]([C:40]([N:14]3[CH2:18][CH:17]4[CH2:19][N:20]([C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[CH2:21][CH:16]4[CH2:15]3)=[O:42])=[N:36][CH:37]=[CH:38][CH:39]=2)[N:29]=[CH:33][CH:32]=1

참가 물질

4

반응물 3

HCID 667422883-[1,2,3]Triazol-2-yl-pyridine-2-carboxylic acid2회HCID 178451519HCID 178451519, 화합물HCID 178524291HCID 178524291, 화합물

생성물 1

HCID 86669169tert-Butyl 5-(3-(2H-1,2,3-triazol-2-yl)picolinoyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

실험 절차

tert-Butyl 5-(3-(2H-1,2,3-triazol-2-yl)picolinoyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate was prepared in a manner analogous to Intermediate 59 substituting 3-[1,2,3]triazol-2-yl-pyridine-2-carboxylic acid (Intermediate 72) for 2-(4H-[1,2,4]triazol-3-yl)-benzoic acid. MS (ESI) mass calculated for C19H24N6O3, 384.19; m/z found, 385.1.

출처 및 근거

ORD 기록
ord-946c7527b05b49ebb847a39c85b16ebc
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09079911B2

연결된 노트

불러오는 중…