HCID 67086543, 화합물 → 3-Methyl-2-(1H-1,2,3-triazol-1-yl)benzoic acid

반응식

[CH3:1][C:2]1[C:3]([N:11]2[N:15]=CC=N2)=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6].CC1C(N2N=CC=N2)=[C:19](C=CC=1)[C:20]#[N:21]>>[CH3:1][C:2]1[C:3]([N:11]2[CH:19]=[CH:20][N:21]=[N:15]2)=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6]

참가 물질

반응물 2

HCID 67086543HCID 67086543, 화합물

HCID 670868833-Methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

생성물 1

HCID 670869453-Methyl-2-(1H-1,2,3-triazol-1-yl)benzoic acid

실험 절차

The title compound was prepared in a manner analogous to Intermediate 82, substituting 3-methyl-2-(1H-1,2,3-triazol-1-yl)benzonitrile for 3-methyl-2-(2H-1,2,3-triazol-2-yl)benzonitrile. 1H NMR (500 MHz, CDCl3): 8.17 (s, 1H), 7.94 (s, 1H), 7.69 (d, J=6.8 Hz, 1H), 7.65 (d, J=7.7 Hz, 1H), 7.63-7.56 (m, 1H), 2.06 (s, 3H).

출처 및 근거

ORD 기록: ord-ecd4d18a770449f381656cbaf13423a4
출처 데이터셋: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09079911B2

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