Benzyl methyl(15-phenylpentadec-5-en-1-yl)carbamate → N-methyl-15-phenylpentadecane-1-amine

HRID 1525801노트

반응식

HRID 1525801 반응식
[CH3:1][N:2]([CH2:13][CH2:14][CH2:15][CH2:16][CH:17]=[CH:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)C(=O)OCC1C=CC=CC=1>C(O)C.[C].[Pd]>[CH3:1][NH:2][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1

참가 물질

4

반응물 1

HCID 86722744Benzyl methyl(15-phenylpentadec-5-en-1-yl)carbamate

생성물 1

HCID 86722746N-methyl-15-phenylpentadecane-1-amine수율 65.4%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

Compound 15 (2.6 g) was dissolved in ethanol (20 mL) and 5% palladium carbon (260 mg) was added thereto, followed by stirring at room temperature for 3.5 hours under hydrogen atmosphere. The reaction solution was replaced with argon atmosphere, filtered with Celite (brand name) and concentrated under reduced pressure to obtain the title compound (1.2 g) having the following physical property values.

후처리

  1. filtrationfiltered with Celite (brand name)
  2. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-7150da1bcaca4e0598449b3849a594d1
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09085523B2

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