3-Cyclopropylprop-2-yn-1-ol → 5-((3-Cyclopropylprop-2-yn-1-yl)oxy)picolinic acid

반응식

[OH:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([O:10]C)=[O:9])=[N:6][CH:7]=1.[CH:12]1([C:15]#[C:16][CH2:17]O)[CH2:14][CH2:13]1>>[CH:12]1([C:15]#[C:16][CH2:17][O:1][C:2]2[CH:3]=[CH:4][C:5]([C:8]([OH:10])=[O:9])=[N:6][CH:7]=2)[CH2:14][CH2:13]1

참가 물질

반응물 2

HCID 27937573-Cyclopropylprop-2-yn-1-ol

HCID 4715126Methyl 5-hydroxypyridine-2-carboxylate

생성물 1

HCID 904013505-((3-Cyclopropylprop-2-yn-1-yl)oxy)picolinic acid

실험 절차

The title compound was synthesized analogously according to Method KS starting from methyl 5-hydroxypicolinate (Molbridge) and 3-cyclopropylprop-2-yn-1-ol. MS m/z: 218 (M+H).

출처 및 근거

ORD 기록: ord-7537ef24034849ef8791788505a58a20
출처 데이터셋: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09085576B2

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