Ethyl bromopyruvate → Ethyl 2-(difluoromethyl)thiazole-4-carboxylate
반응식
[F:1][CH:2]([F:6])[C:3](=[S:5])[NH2:4].Br[CH2:8][C:9](=O)[C:10]([O:12][CH2:13][CH3:14])=[O:11]>CCO>[F:1][CH:2]([F:6])[C:3]1[S:5][CH:8]=[C:9]([C:10]([O:12][CH2:13][CH3:14])=[O:11])[N:4]=1참가 물질
4
반응 조건
- 온도
- 50 °C
실험 절차
A mixture of 2,2-difluoroethanethioamide (1.023 g, 9.21 mmol) and ethyl bromopyruvate (1.150 mL, 9.21 mmol) in EtOH (20 mL) was heated to 50° C. for 2 h.
출처 및 근거
- ORD 기록
- ord-edcd9721cc3c4bfbbf3c551fd25dcd55
- 출처 데이터셋
- uspto-grants-2015_07
- 특허 번호
- US09085576B2
반응 노트
불러오는 중…