6-Methoxy-1H-indole-3-carboxylic acid → 3-Isocyanato-6-methoxy-indole-1-carboxylic acid amide

반응식

[CH3:1][O:2]C1C=C2C(C(C(O)=O)=CN2)=CC=1.[N:15]([C:18]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[N:20]([C:27]([NH2:29])=[O:28])[CH:19]=1)=[C:16]=[O:17]>>[N:15]([C:18]1[C:26]2[C:21](=[CH:22][C:23]([O:2][CH3:1])=[CH:24][CH:25]=2)[N:20]([C:27]([NH2:29])=[O:28])[CH:19]=1)=[C:16]=[O:17]

참가 물질

반응물 2

HCID 177509566-Methoxy-1H-indole-3-carboxylic acid

HCID 575200853-Isocyanato-indole-1-carboxylic acid amide

생성물 1

HCID 866737883-Isocyanato-6-methoxy-indole-1-carboxylic acid amide

실험 절차

was prepared from 6-methoxy-indole-3-carboxylic acid using the protocol described for the preparation of 3-isocyanato-indole-1-carboxylic acid amide scheme A1.

출처 및 근거

ORD 기록: ord-4ab3a084845f4288b97cbad109eba2a6
출처 데이터셋: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09085555B2

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