Indolizine-1,3-dicarboxylic acid 1-benzyl ester → 3-Isocyanato-indolizine-1-carboxylic acid benzyl ester

반응식

[CH2:1]([O:8][C:9]([C:11]1[CH:12]=[C:13](C(O)=O)[N:14]2[C:19]=1[CH:18]=[CH:17][CH:16]=[CH:15]2)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC1C=C2C(=CC=1)[N:32]([C:36](N)=[O:37])C=C2N=C=O)C=C>>[CH2:1]([O:8][C:9]([C:11]1[CH:12]=[C:13]([N:32]=[C:36]=[O:37])[N:14]2[C:19]=1[CH:18]=[CH:17][CH:16]=[CH:15]2)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 68283859Indolizine-1,3-dicarboxylic acid 1-benzyl ester

HCID 866737945-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide

생성물 1

HCID 866738133-Isocyanato-indolizine-1-carboxylic acid benzyl ester

실험 절차

The title compound was prepared from indolizine-1,3-dicarboxylic acid 1-benzyl ester using the protocol described in step E scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide.

출처 및 근거

ORD 기록: ord-acdf7132f0974f72b02c9dd73965ec50
출처 데이터셋: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09085555B2

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