7-chloro-1H-indole-3-carbaldehyde → HCID 71009429, 화합물

HRID 1527214노트

반응식

HRID 1527214 반응식
[Cl:1]C1C=CC=C2C=1NC=C2C=O.[C:13]([C:16]1[C:24]2[C:19](=[CH:20][CH:21]=[C:22](Cl)[CH:23]=2)[N:18]([CH2:26][C:27]([OH:29])=[O:28])[CH:17]=1)(=[O:15])[NH2:14]>>[C:13]([C:16]1[C:24]2[C:19](=[C:20]([Cl:1])[CH:21]=[CH:22][CH:23]=2)[N:18]([CH2:26][C:27]([OH:29])=[O:28])[CH:17]=1)(=[O:15])[NH2:14]

참가 물질

3

반응물 2

HCID 6439587-chloro-1H-indole-3-carbaldehydeHCID 68283591HCID 68283591, 화합물

생성물 1

HCID 71009429HCID 71009429, 화합물

실험 절차

was prepared from 7-chloro-1H-indole-3-carbaldehyde [1008-07-7] using similar protocols as described in Scheme A11 for the preparation of (3-carbamoyl-5-chloro-indol-1-yl)-acetic acid. White solid. MS (LC/MS): 253 [M+H]+, 505 [2M+H]+; tR (HPLC conditions b): 3.32 min.

후처리

  1. custom3.32 min.

출처 및 근거

ORD 기록
ord-4e637870330846cd9aaf67b92924df26
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09085555B2

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