HCID 89525566, 화합물 → C-(5-methylfuran-2-yl)-C-(3-methyloxetan-3-yl)methylamine
반응식
[N:1]([CH:4]([C:11]1([CH3:15])[CH2:14][O:13][CH2:12]1)[C:5]1[O:6][C:7]([CH3:10])=[CH:8][CH:9]=1)=[N+]=[N-].[H][H]>C(O)C.[Pd]>[CH3:10][C:7]1[O:6][C:5]([CH:4]([NH2:1])[C:11]2([CH3:15])[CH2:12][O:13][CH2:14]2)=[CH:9][CH:8]=1참가 물질
5
실험 절차
A solution of 1.68 g (8 mmol, 1 eq) of 2-[azido-(3-methyloxetan-3-yl)methyl]-5-methylfuran in 30 ml of ethanol in the presence of 252 mg (15% by weight) of palladium on carbon at 10% was stirred at hydrogen atmospheric pressure for 3 hours. The reaction medium was filtered and the filtrate was evaporated. 1.42 g of C-(5-methylfuran-2-yl)-C-(3-methyloxetan-3-yl)methylamine were obtained in the form of a greenish oil. Yield=98%.
후처리
- filtrationThe reaction medium was filtered
- customthe filtrate was evaporated
출처 및 근거
- ORD 기록
- ord-0f95d1c70e0145198158ee2e451d261a
- 출처 데이터셋
- uspto-grants-2015_07
- 특허 번호
- US09090596B2
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