Methyl isobutyrate → Methyl 3-[3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl]-2,2-dimethyl-3-oxopropanoate

HRID 1528334노트

반응식

HRID 1528334 반응식
[CH3:1][CH:2]([CH3:7])[C:3]([O:5][CH3:6])=[O:4].[CH:8]1([CH2:11][O:12][C:13]2[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=2[O:22][CH:23]([F:25])[F:24])[C:16](Cl)=[O:17])[CH2:10][CH2:9]1>>[CH:8]1([CH2:11][O:12][C:13]2[CH:14]=[C:15]([C:16](=[O:17])[C:2]([CH3:7])([CH3:1])[C:3]([O:5][CH3:6])=[O:4])[CH:19]=[CH:20][C:21]=2[O:22][CH:23]([F:25])[F:24])[CH2:10][CH2:9]1

참가 물질

3

반응물 2

HCID 11039Methyl isobutyrateHCID 120473303-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoyl chloride

생성물 1

HCID 66616523Methyl 3-[3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl]-2,2-dimethyl-3-oxopropanoate

실험 절차

Prepared analogously as described for example D1 using methyl 2-methylproponate and 3-cyclopropylmethoxy-4-difluoromethoxybenzoyl chloride as starting compounds.

후처리

  1. customPrepared analogously

출처 및 근거

ORD 기록
ord-ac1a39399b724286b776e653284d788e
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09090597B2

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