1,2-Dibromoethane → 1-(5-Bromopyridin-2-yl)cyclopropane-1-carbonitrile

HRID 1528564노트

반응식

HRID 1528564 반응식
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]#[N:10])=[N:6][CH:7]=1.Br[CH2:12][CH2:13]Br>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([C:9]#[N:10])[CH2:13][CH2:12]2)=[N:6][CH:7]=1

참가 물질

3

반응물 2

HCID 78391,2-DibromoethaneHCID 29927881(5-Bromopyridin-2-yl)acetonitrile

생성물 1

HCID 534029901-(5-Bromopyridin-2-yl)cyclopropane-1-carbonitrile수율 88%

실험 절차

Alternatively, the title compound was prepared from (5-bromo-pyridin-2-yl)-acetonitrile and 1,2-dibromoethane following a procedure analogous to that described in Step 3 for Intermediate 4. Yield: 88% of theory.

출처 및 근거

ORD 기록
ord-5c882792113d4bbd9aff6683d8b7fac0
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09090605B2

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