1,2-Dibromoethane → 2-Chloro-5-(1-methanesulfonylcyclopropyl)pyridine

HRID 1528588노트

반응식

HRID 1528588 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][S:9]([CH3:12])(=[O:11])=[O:10])=[CH:4][N:3]=1.Br[CH2:14][CH2:15]Br>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([S:9]([CH3:12])(=[O:11])=[O:10])[CH2:15][CH2:14]2)=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 78391,2-DibromoethaneHCID 457912372-Chloro-5-((methylsulfonyl)methyl)pyridine

생성물 1

HCID 866961442-Chloro-5-(1-methanesulfonylcyclopropyl)pyridine수율 52%

실험 절차

The title compound was prepared from 2-chloro-5-methanesulfonylmethyl-pyridine and 1,2-dibromoethane following a procedure analogous to that described in Step 3 for Intermediate 4. Yield: 52% of theory; Mass spectrum (ESI+): m/z=232/234 (Cl) [M+H]+.

출처 및 근거

ORD 기록
ord-1cb6425b08094207ad4f0ba585da47f0
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09090605B2

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