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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1528906생성일: 2026년 10월 26일

4-[3-(Trifluoromethyl)phenyl]butan-2-one → 1-(4'-{3-Methyl-4-[1-methyl-3-(3-trifluoromethyl-phenyl)-propylamino]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1528906

반응식

참여 물질

역할이름HCID투입량
반응물4-[3-(Trifluoromethyl)phenyl]butan-2-oneHCID 13339059—
반응물1-[4'-(4-Amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66577195—
생성물1-(4'-{3-Methyl-4-[1-methyl-3-(3-trifluoromethyl-phenyl)-propylamino]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl esterHCID 66581771—

반응 단계

Prepared according to the procedure described in Example 24, Step 1, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 4-(3-trifluoromethyl-phenyl)-butan-2-one.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09090573B2
출처 데이터셋uspto-grants-2015_07
ORD IDord-8444b0f9401e41b2b93506808d23c56d
출처 메모uspto-grants-2015_07