4-(3,3,3-Trifluoropropyl)phenol → HCID 21252690, 화합물
반응식
[H][H].[F:3][C:4]([F:15])([F:14])[CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1>C(O)(C)C.[Rh]>[F:3][C:4]([F:14])([F:15])[CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][CH:10]([OH:13])[CH2:9][CH2:8]1참가 물질
5
실험 절차
At 50° C. and 150 bar hydrogen pressure, 40.7 g of 4-(3,3,3-trifluoropropyl)phenol in 800 ml of isopropanol were hydrogenated using rhodium on carbon as catalyst for 20 h. The catalyst was filtered off and the reaction solution was concentrated, to give the title product as a colourless solid which was reacted further without any purification.
후처리
- customAt 50° C.
- customfor 20 h
- filtrationThe catalyst was filtered off
- concentrationthe reaction solution was concentrated
출처 및 근거
- ORD 기록
- ord-7060604328b04fffb52ac74b1780025b
- 출처 데이터셋
- uspto-grants-2001_03
- 특허 번호
- US06197729B1
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